Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
Print ISSN : 0300-9173
Effect of Sex, Age, Smoking and Alcohol on Serum Levels of Apoprotein in Healthy Adults
The Application of Robust and Exploratory Data Analysis
Masahiro KawanishiShigenobu MatsuokaMasataka HiraokaGen KonemoriKoki TakataTetsuhiko WatanabeHiromasa OotaniGoro Kajiyama
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1988 Volume 25 Issue 1 Pages 28-37

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Abstract
In order to investigate various influences to serum levels of apoproteins in healthy adults, we applied box-plots which are fundamental methods of exploratory data analysis and robust regression analysis. Serum concentrations of apoprotein A-I, A-II, B, C-II, C-III and E were measured by a single radial immunodiffusion method. The subjects consist of 179 males and 60 females aged 30-69 who are the staff and the retirees of Hiroshima University. The following results were obtained: 1. The levels of apoprotein A-II (aged 40-49), B (aged 30-39), C-II (aged 40-49) and C-III (aged 30-39, 40-49) in male were significantly higher than those in female. 2. It was observed that the levels of apoprotein-B, C-II and C-III in male, and A-II, B and E in female elevated with age. 3. Drinkers had higher levels of apoprotein A-I, A-II and C-III than non-drinkers in male. 4. Cigarette smokers had higher levels of apoprotein C-II and C-III than non-smokers in male. 5. Overweight adults had higher levels of apoprotein A-II, B, C-II, C-III and E in male and apoprotein-E in female than adults who are not overweight.
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