Intracystic Infusion Therapy of Minocycline Hydrochloride for Benign Hepatic Cysts

Abstract

This paper describes ultrasonically-guided infusion of minocycline hydrochloride solution (MINO infusion therapy) in benign nonparasitic cysts of the liver. MINO infusion therapy was performed in 7 large hepatic cysts and successful results were obtained in 6 lesions. The infusion procedure in the initial 4 hepatic cysts a 7 Fr catheter was placed into the cyst and MINO solition was left in the cyst according to the procedure of ethanol infusion theray. In the most recent 2 cases the cyst was punctured with a 21G needle, washed with physiologic saline and then infused MIND solution without placement of an indwelling drainage tube. This modified procedure is simple and safe and also yields a good therapeutic result. MINO infusion therapy for benign hepatic cyst is very useful and the modified procedure can be performed safely in elderly patients and in patients with several complications.