Abstract
Twenty five different stocks of wild-type Drosophila melanogaster were treated with nitromin (methyl bis-β-chloroethyl-amine N-oxide hydrochloride). The treatment was to immerse 70 hours old larvae in a 2% solution of nitromin for 3 hours in dark room. Such treatment proved to be effective in producing phenocopies in varied organs of the fly. Anomalies were found in such organs as the compound eye, wing, leg, abdomen, thorax, antenna, proboscis and ocellus. Of these, the compound eye was the organ most frequently and most severely affected. However, it was marked that different stocks of the flies behaved differently in response to the same treatment of nitromin. Differences of the responses were conspicuous in the rate of adult hatching, in the kind of the organs affected and the degrees of anomalies produced. In these respects there was a general tendency that responses of the individual stocks of the fly were definite though they were differed markedly between different stocks. Such differences of the response may be referred to differences of the genetical constitution possessed by different stocks of the wild-type flies examined.