The Japanese Journal of Genetics
Online ISSN : 1880-5787
Print ISSN : 0021-504X
ISSN-L : 0021-504X
Chromosomal Alteration and the Development of Tumors
VI. Difference in Invasiveness of the Diplo- and Tetraploid Cells of the Yoshida Sarcoma
Tosihide H. YOSIDAShigekatsu TSUJI
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1960 Volume 35 Issue 12 Pages 377-381

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Abstract
After the Yoshida sarcoma was transplanted into B-strain rats, one of them developed a tumor which was characterized by having a high percentage of tetraploid tumor cells.
Using this tumor material, the facility of invading the lung tissue of the diplo-and tetraploid karyotypes, was examined. The result of observations indicates that the infiltration ability of tetraploid tumor cells into the lung tissue was much stronger than that of the diploid cells. On the other hand, the vast majority of tumor cells forming the solid tumor which had developed in the peritoneal cavity were of the diploid type.
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© The Genetics Society of Japan
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