Abstract
An attempt was made to demonstrate a change in the electrophoretic pattern of tyrosinase in the neo-natal stage in mice with different genotypes at a locus. In agouti as well as non-agouti animals, both T1 and T2 bands appeared on one or two days after birth and persisted until the 9th to 10th day after which only the T1 band remained. On the other hand, only the T1 band was observed in the yellow mice throughout the post-natal stages. It is conceivable that either of the processing steps, T1 to T2 or the nascent tyrosinase to T2 is blocked by the product of Ay gene, resulting in phaeomelanin formation.
