THE THIRD ALLELE OF SUPERNATANT ISOCITRATE DEHYDROGENASE OF HOUSE MOUSE, Id-1^c, ORIGINATES FROM ASIAN CONTINENT

Abstract

Electrophoretic survey of Id-1 alleles in the Japanese wild mouse, Mus musculus molossinus, revealed the existence of four alleles, Id-1^a, Id-1^b, Id-1^c and Id-1^d. Two alleles, Id-1^c and Id-1^d, are not present in European and American wild mouse populations, had overall frequencies of .138 and .006, respectively, in the Japanese mouse. The Id-1^b allele was most frequent (.782) and Id-1^a was relatively rare (.074). Geographically, the northern populations possess mostly Id-1^b allele (.985), while Id-1^a, Id-1^b, and Id-1^c alleles are common in the southern regions. This geographical distribution can be explained by the multiple migration hypothesis of the wild mouse into Japan through two southern routes. This explanation is partly supported by the presence of Id-1^c allele in the Asian house mice from the Philippines and Thailand.