Genetic studies of RBC catalase in the RAT

Rattus norvegicus

Abstract

A polymorphism of RBC catalases was found by starch gel electrophresis among inbred strains of rats. The slow migrating banding pattern (CS-1B) is dominant over the fast migrating banding pattern (CS-1A) and in progeny made by backcrossing F₁ hybrids with CS-1A type parental strain the two types segregated 1:1. The designation Cs-1 locus, with two alleles (Cs-I^a, Cs-1^b), is tentatively proposed. The Cs-1 locus is not linked with the linkage group (LG) I, II, IV, V, VI, VIII and the LG containing Amy-1. The Cs-1^b allele is distributed among several common inbred strains of rats derived from the so-called Wistar strain in Japan and its origin is discussed.