Studies on the sex-specific lethals of Drosophila melanogaster.
VIII. Enhancement and suppression of Sxl expression by mle(3)132
1984 Volume 59 Issue 4 Pages 335-348
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1984 Volume 59 Issue 4 Pages 335-348
Interactions among three sex-specific lethals, da, Sxlf#1 and mle(3)132 of Drosophila melanogaster were studied as to the effects on viability and sex transformation. Six crosses involving these mutants were made. The results showed that mle(3)132 interacts with the da-Sxl system both maternally and zygotically. These two effects are opposite in action. Maternal mle(3)132 enhances both lethal and sex transforming actions of the da-Sxl system. Zygotic mle(3)132, on the contrary, suppresses the lethal action. Roles of these three sex-specific lethals are discussed in relation to sex determination and dosage compensation.
