1996 Volume 7 Pages 226-227
Experimental evidence implying that complementary DNA strands encode amino acidswhich exhibit complementary hydrophobic characteristics has led us to the inspection of sense-antisense homology in several hundreds of proteins recorded in the PDB. We present here partial results of this analysis which relate localized peculiar structural characteristics of proteins to the senseantisense homology boxes found in the primary sequences. A further analysis is performed in order to determine whether these sense-antisense homology boxes, if existent within the protein, are encoded by unique sequences of codons in the DNA. We also make here a progress report about the methodology and the results obtained so far.
