Uric acid research
Online ISSN : 2187-0098
Print ISSN : 0388-4120
ISSN-L : 0388-4120
The Xanthine Stone Formation in Lesch-Nyhan Syndrome by Allopurinol
Koji HIRAISHI, Akira YAMAMOTO, Hiroshi YAMAMOTO, Haruhiro TSUJIMURA, Kenzo FUJIMOTO
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1980 Volume 4 Issue 1 Pages 77-82

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Abstract
A 14-year-old boy with Lesch-Nyhan syndrome was treated for hyperuricemia by allopurinol.3 years later he developped many stones and the stone analysis revealed xanthine. Iatrogenic xanthine stone formation by allopurinol are reported in Lesch-Nyhan syndrome and in patients with progressive cancer.
Etiology and prevention of xanthine stone formation is briefly discussed.
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© Japanese Society of Gout and Nucleic Acid Metabolism
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