Abstract
Strenuous exercise is known to cause temporary exercise-induced hyperuricemia. In this study, we examined whether long term hyperuricemia is caused by continuous exercise in 11 male longdistance and marathon runners (age range,20-42 years) by measuring serum uric acid level before and after a one-month intensive training period (“October Run”).
The mean daily running distance during this month(23.9±2.5km)was about 2.5 times that during the previous month(9.4±2.0km). In the following month(November), the mean daily running distance decreased to 10.4±1.5km during the first 2 weeks and 9.1±1.8km druing the last 2 weeks. The energy intake during the intensive training period was about 1.2 times that before the periodd, but no increase in body weight was observed, suggesting that the balance between energy intake and energy expenditure was maintained.
The mean serum uric acid levels was 6.1±0.2mg/dl immediately before the training Period,5.6±0.2mg/dl immediately after the period,5.4±0.3mg/dl 2 weeks thereafter. and 5.3±0.4mg/dl 4 weeks thereafter. The serum uric acid level immediately after and 2 and weeks after the training period was significantly reduced (p≤0.05) compared with that before the period.
These findings suggest that the serum uric acid level is not increased by continuous vigorous exercise despite an increase in the energy intake if this increase is balanced with the energy expenditure and produces no weight gain.
