Effect of titanium ion on cell viability of macrophage-like RAW264 cells

Abstract

We evaluated the cell viability of macrophage-like RAW264 cells cultured in media mixed with diluted solutions of HCl solution containing titanium ions. When cultured in 1000 times diluted 20% HCl solution, the cell viability declined to 70% relative to the control. When cultured in 1000 times diluted 20% HCl solution containing 1000 ppm titanium ions, the cell viability decreased to 55% relative to the control. It was hinted that titanium ions formed complex, which was phagocytized by the cell, leading to reduced cell viability.