Next Generation Calcium Phosphate-based Biomaterials

Abstract

It has been close to a century since calcium phosphate materials were first used as bone graft substitutes. Numerous studies conducted in the last two decades have produced a wealth of information on the chemisitry, in vitro properties, and biological characteristics of granular calcium phospates and calcium phospate cement biomaterials. A in depth analysis of several key areas of calsium phosphate cement properties are presented with the aim of developing strategies that could lead to break-through improvements in the functional efficacies of materials.