Adsorption of an Antibacterial Protein onto Dental Material-Related Surfaces Investigated by QCM Method

Takashi Nezu; Kaori Sasaki; Setsuo Saitoh; Masayuki Taira; Yoshima Araki

doi:10.14832/gsjsdmd.2007f.0.261.0

50th General Session of the Japanese Society for Dental Materials and Devices in conjunction with International Dental Materials Congress 2007

Session ID : P-218

DOI https://doi.org/10.14832/gsjsdmd.2007f.0.261.0

Conference information

Host: The Japanese Society for Dental Materials and Devices

Poster Presentation

Adsorption of an Antibacterial Protein onto Dental Material-Related Surfaces Investigated by QCM Method

*Takashi Nezu, Kaori Sasaki, Setsuo Saitoh, Masayuki Taira, Yoshima Araki

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Keywords: lysozyme, adsorption, QCM

CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract

Adsorption behavior of lysozyme that is rich in sariva and known as an antibacterial protein, onto some dental material-related subustrates was studied by QCM method. Au substrate showed a strong affinity for Lyz in any condition studied (pH 3 or 5, C_s = 0 or 50 mM). Oxide substrates (SiO₂, TiO₂) showed a pH dependent adsorption that could also be affected by salt, which indicated an electrostatic attraction between the surfaces and Lys. The current QCM study showed that Lyz was expected to be adsorbed onto gold alloys, porcelains and titanium structures, partly by an electrostatic interaction.

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