Abstract
In this study, we investigated the chemical property and biological response of titanium with different ages. Machined, acid etched and sandblasted titanium surfaces were prepared. Immediately (fresh), 3 days, 1 week and 1 month after the preparation, the surfaces were examined for hydrophilicity and biological response. The amount of albumin adsorbed to the 1 month old acid-etched surface was 30% of that for the fresh acid-etched surface. The amounts of protein adsorption of the 1 month-old surfaces were lower by 30% than for the fresh surfaces even after 24 hour incubation. Biological response capacity of titanium drops over time.