Abstract
Through the mediation of the gut-brain axis, sleep quality has a bidirectional effect on the gut microbiota. Using fecal T-RFLP flora analysis, we have found that improving sleep quality leads to changes in the gut microbiota. In particular, we observed an increase in short-chain fatty acid (SCFA)-producing bacteria such as Bacteroidota, Oscillospiraceae, and Lachnospiraceae. The microbiota of persons with poor "sleep quality" is similar to the pattern of dementia patients, and may approach the pattern of healthy people as "sleep quality" improves. In this report, we picked up major bacteria that are expected to be related to sleep quality and reviewed the literature. It seems important to avoid dysbiosis and maintain the dominance of SCFA-producing bacteria in order to maintain good "sleep quality" and hopefully prevent the progression of dementia.
