Abstract
The main cause of glycative stress is an excess of aldehydes, and it is particularly important to suppress postprandial hyperglycemia, which is involved in the production of aldehydes. This is because many types of aldehydes are produced in a chain reaction following postprandial hyperglycemia. In order to understand the conditions for the occurrence of postprandial hyperglycemia, we have performed many blood glucose tests. Initially, we measured blood glucose via fingertip punctures, but in 2019, we introduced a method of monitoring blood glucose levels for two consecutive weeks using the FreeStyle Libre (Abbott). This has dramatically reduced the burden and pain of subjects by eliminating frequent pain and bleeding in the fingertips. In recent years, the model has been changed from Libre Pro to Libre 2, and the measurement interval has been shortened from the conventional 15 minutes to 1 minute. In this study, we compared the difference in the "postprandial blood glucose change curve" between the new and old models. As a result, it was shown that changes in blood glucose levels can be detected with high sensitivity even when sugar-containing sweetened beverages are consumed during meals. In our laboratory, we plan to conduct blood glucose level tests using the new model (Libre 2) in the future.
