Four Cases of Tracheal Adenoid Cystic Carcinoma

Abstract

Background. Tracheal adenoid cystic carcinoma (TACC) is the most common type of cancer among tracheal tumors. However, the findings of molecular analyses for TACC have rarely been reported. Case. Case 1: A woman in her 80s complaining of dyspnea on effort was found to have a 1.3-cm tracheal tumor just below the vocal folds and a solitary pulmonary metastasis on computed tomography (CT). After tracheal tumor resection with rigid bronchoscopy, radiation therapy was performed. Subsequently, lobectomy was performed. Case 2: A woman in her 40s complaining of wheezing was found to have 6-cm upper tracheal stenosis due to a tumor on CT. After tumor resection and Dumon^® stent insertion with rigid bronchoscopy, radiation therapy was performed. Case 3: A woman in her 40s complaining of dyspnea was found to have 6.6-cm upper tracheal stenosis due to a circumferential tumor and invasion into the surrounding tissue on CT. She underwent the same treatments as Case 2. Case 4: A man in his 40s complaining of wheezing was found to have 5.5-cm lower and carinal tracheal stenosis induced by a tumor on CT. The same treatments as in Cases 2 and 3 were performed. All four cases were diagnosed with TACC by a histopathological study. Conclusion. We report our clinical experiences with four cases of TACC and a molecular analysis.