2025 Volume 65 Issue 4 Pages 286-290
Background. Thymic carcinoids are rare, and their pathogenesis remains largely unknown. According to the World Health Organization (WHO) classification, most thymic carcinoids are atypical, and there are few reports on distant metastasis or surgical treatment of typical carcinoids. Case. An 81-year-old man was referred to our department in May X because of an abnormal shadow on chest radiography. On plain chest computed tomography (CT), a 6.5-cm tumor was observed in the anterior mediastinum, and 18F-fluorodeoxyglucose positron emission tomography/CT revealed hyperintensity in the same area. This hyperintensity suggested the presence of multiple bone metastases. An echo-guided needle biopsy of the anterior mediastinal mass was performed, and the patient was diagnosed with a thymic typical carcinoid. As there is no established treatment strategy for stage IV thymic typical carcinoid, we performed mediastinal tumor resection for local control and made a histopathological diagnosis of the entire tumor. The postoperative histopathological diagnosis was the same as that of the needle biopsy. Postoperatively, everolimus was administered as systemic chemotherapy. Currently, seven months after surgery, there are no signs of new lesions or an increase in metastatic lesions. Conclusion. This report highlights a case of stage IV thymic typical carcinoid with multiple bone metastases in which multidisciplinary treatment, including surgery, was performed.
