Abstract
Sixteen cases (8 autopsied and 8 resected specimens) of irradiated primary lung cancer have been studied roentgenologically and, morpho-histologically with special reference to the tumour and surrounding tissues using the paper mounted large lung section and microscopy. The purpose of this study is to analyze the roent-genological features of the tumour and thier surrounding tissues and the morpho-histological findings after the cobalt 60 radiation therapy.
The following results have been obtained.
1) Roentgenological findings of the tumour and surrounding tissues show diffuse homogeneous densities consist of resolving localized compressive atelectasis, radiation pneumonia-fibrosis, fibrosis of alveolar septa and secondary infection, metastasis, atelectasis, congestion and hemorrhage in the lung.
2) Linear and bronchial tree like shadows radiated from the tumour to the peripheral lung fields consist of proliferation and fibrotic retracted interstitium of the tumour and fibrotic change of blood vessels, lymphangitis carcinomatosa and indentated thickened pleura.
Finally the changes of cancer cells as a result of irradiation were discussed.
