Abstract
Lung ventilation study by the continuous inhalation of 81mKr gas from a 81Rb-81mKr generator and lung perfusion study with 99mTc-MAA were performed on 36 patients suffering from bronchogenic carcinoma.
The patients were measured in a sitting position using a scintillation camera in conjunction with a data processor.
In a same patient of pulmonary carcinoma 81mKr technique and 133Xe study were demonstrated for comparison of ventilation imaging.
There were 13 cases with discrepancy between ventilation with 81mKr gas and perfusion with 99mTc-MAA. Eight out of 13 patients showed more impaired perfusion (V/Q>1.2) and 5 out of 13 patients showed more severe ventilation (V/Q<0.8). We discussed the ventilation / perfusion mismatching cases.
Eight patients were studied before and after irradiation. The ventilation-perfusion ratios of the affected lung have markedly improved after radiation therapy.
Lung ventilation and perfusion studies with 81mKr gas and 99mTc-MAA easily allowed quantitative controls of radiation therapy.
