Abstract
A case of a 68-year-old asbestos worker, with a history of 34 years exposure, with double primary lung cancer was reported. Chest X-ray film showed bilateral tumorous shadows. Sputum cytology and needle biopsy revealed double primary bronchogenic carcinoma. One was squamous cell carcinoma and the other oat cell carcinoma.
The autopsy revealed the oat cell carcinoma to originate in the periphery of the right upper lobe (Si a), and the squamous cell carcinoma in the periphery of the left lower lobe (S10), associated with moderate asbestosis, squamous metaplasia and a tumorlet lesion.
A clinico-pathological study of 8 cases of multiple primary bronchogenic carcinoma associated with asbestos exposure, including the present case, suggested the possibility of multicentric occurrance of lung cancer associated with asbestos exposure and smoking.