Abstract
The clinical and pathological findings of double primary cancer involving lung cancer are important in terms of carcinogenesis, cancer immunity and surgical therapy.
Seven cases out of 156 cases involving lung cancer were asynchronous, and another seven cases were synchronous double primary cancer of the lung. In the metachronous double cancer cases, the site of the initial tumor was the stomach in three, the uterine cervix in two and the larynx and breast in one each. All were operated on two to twenty-six year previously.
The other primary tumors in cases of synchronous double cancer were located in the prostate in two cases and there was one each in the one hepatic duct, stomach, skin, liver, and lung. In these seven cases only two were diagnosed clinically, and five were detected at autopsy.
Synchronous and asynchronous double primary cancer cases involving lung cancer constituted 14 cases out of 156, 7 cases were synchronous (4.5%), and 5 cases (11%) out of 45 autopsy cases were synchronous detected at autopsy.
These incidence rates are higher than those previously reported and higher than the occurrence of cancer in normal adults.
