Abstract
A 49-year-old female was admitted to our hospital with chief complaints of dry cough and exertional dyspnea. From the diffuse miliary chest X-ray shadow, we suspected interstitial pneumonia. We obtained a definitive diagnosis of pulmonary metastasis of papillary adenocarcinoma on the third transbronchial lung biopsy (TBLB) procedure. The primary lesion was suspected in the thyroid, however there were no abnormal findings except diffuse T1C1 uptake in the lung on the scintigram. Autopsy revealed the primary lesion to be poorly differentiated papillary adenocarcinoma of the thyroid. Widespread metastasis including in the lung were found. It is suggested that TBLB is useful for the differential diagnosis of patients with diffuse disseminated lung shadows. It is also recommended to repeat TBLB to obtain a definitive diagnosis.