Immunosuppressive Acidic Protein (IAP) in The Serum of Primary Lung Cancer Patients

Abstract

Serous immunosuppressive acidic protein (IAP) was measured to assess its significance in 96 cases with primary lung cancer treated with radiotherapy at our department.
IAP positivity was 73.9% in all cases, however the distribution of IAP levels showed various degrees corresponding to the histologic type, and the positive rate of adenocarcinoma, which was lower than of any other histological type, was 46.1%.
There was no obvious correlation between clinical stage and IAP level, although elevation of the IAP level could be seen in the group of advanced cases with squamous and large cell carcinoma.
The combination of IAP level and PPD reaction might prove to be helpful in indicating prognosis. The fluctuation of the IAP level reflected the clinical course and an IAP level of 1000 g/ml seemed to have prognostic implications.