Suspected Multiple Primary Carcinoma in a Case of Squamous Cell Carcinoma of the Lung with Metastasis to the Stomach

Abstract

A 62-year-old man was admitted to our hospital with cough and sputum. Based on radiographic and bronchoscopic findings, multiple bilateral primary carcinoma of the lung was suspected clinically. The upper gastrointestinal endoscopic examination showed a Borrmann- II type metastatic lesion in the gastric corpus. The histologic diagnosis of these lesions was moderately differentiated squamous cell carcinoma. These lesions were resistant to radiation and chemotherapy. The patient's clinical condition worsened progressively with controllable anemia. Nine months after admission the patient died and the autopsy findings were as follows; multiple primary lung carcinoma (squamous cell carcinoma), metastatic tumors found in stomach, liver, adrenal glands, colon, brain and lymph nodes. Multiple primary lung cancer as well as lung cancer with metastatic gastric tumors, are two very rare pathological entities with a frequency of 1-4% and 2-4% among lung cancer cases, respectively.