Abstract
A 63-year-old man with small cell lung cancer metastatic to the orbit was reported. After 3 courses of chemotherapy he showed a good response on chest roentgenogram, additional radiotherapy 5320 cGy was performed. Ten months after initiation of the treatment, left side blepharoptosis developed, with pain and swelling of the orbit, biopsy of which revealed metastatic small cell carcinoma. Although three courses of chemotherapy with Vindesine 4.5mg (days 1, 8, 15) were effective for the orbital metastasis, he died due to progression of the primary lesion and liver metastasis. Reported cases of lung cancer metastatic to the orbit in Japan were reviewed and the effects of Vindesine on the orbital metastasis in this case were discussed.
