1993 Volume 33 Issue 1 Pages 121-128
Granular cell tumor, the histological origin of which is considered to be myogenic or neurocytegenic, is usually benign and is found in various organs but is rare in the trachea, bronchus, and lung. A case of primary bronchial granular cell tumor in a 53-year-old male with bronchial asthma was detected. He complained of pharyngeal discomfort. Fiberoptic bronchoscopy revealed a whitish elevated lesion at the orifice of the left basal bronchus which had a smooth surface and was partially nodular. Biopsy revealed characteristic pathological findings of granular cell tumor, including numerous eosinophilic granules in the cytoplasm of tumor cells that were positive for PAS stain and S-100 protein. This tumor was diagnosed as primary granular cell tumor of the bronchus. Our case is the 22nd case of granular cell tumor located in the trachea, bronchus or lung reported in Japan. Though granular cell tumor is often surgically resected, we are following up our case carefully as most of them are benign and grow slowly.
