1994 Volume 34 Issue 1 Pages 127-131
A 66-year old man was admitted with hemoptysis. His chest x-ray film revealed a left hilar mass shadow. The cytology of sputum and brushing samples demonstrated the following mixed pattern: 1) some tumor cells had a high nuclear-cytoplasmic ratio and hyperchromatic nuclei; 2) the other cancer cells had a relatively low nuclear-cytoplasmic ratio and varied in size and shape. Mitotic figures were frequently observed. Since it was very difficult to determine the cell type of his tumor on the basis of the cytological findings, a left cervical metastatic lymph node was biopsied. The histopathological, immunohistochemical and electron microscopic findings of this specimen showed LCNEC. To our knowledge, this is the first reported case of LCNEC with various cytological findings.
