1996 Volume 36 Issue 6 Pages 803-807
A case of a 66-year-old man with primary leiomyosarcoma arising in the lung from right main bronchus was reported. The patient consulted with complaints of cough and hemoptysis and an abnormal shadow was found on chest radiograph and cytological examination showed malignant findings. He was admitted to our medical center. Right middle and lower lobectomy was carried out on the suspicious diagnosis of lung cancer. Histologically, the resected specimen disclosed the tumor composed of spindle cells with blunt-ended nuclei and polygonal cells with pleomorphic nuclei. Immunohistological study disclosed that α-smooth-muscle actin was positive and that Vimentin was weakly positive. Ultrastructural findings revealed myofilaments with dense-patch in the cytoplasm of the tumor cells. The patient is alive 19 months postoperatively without any evidence of recurrence or metastasis. Primary pulmonary leiomyosarcoma wasdiagnosed.
