1996 Volume 36 Issue 6 Pages 821-825
A 70-year-old male in whom rheumatoid pneumonitis had been diagnosed six years previously, was admitted because of a coin lesion seen on his annual chest X-ray examination. The lesion was located in left S9 and was cytologically diagnosed as malignant by percutaneous needle biopsy. A left lower lobectomy was performed and the tumor was determined to be a large cell neuroendocrine carcinoma by an immunohistochemical study. Because of vascular invasion, adjuvant chemotherapy was administered. We report this rare case because there have been no reports in the literature on this complication of rheumatoid pneumonitis and large cell neuroendocrine carcinoma.