Indium-mediated Chemical Transformations of the Selected Moieties

Abstract

Indium reagents including indium metal have become of attention due to the moderate reactivity attained under mild conditions. Here are presented indium-mediated transformations such as the tetrahydropyranylation of alcohols and depyranylation, and methyl esterification of carboxylic acids, which are smoothly catalyzed by indium(III) triflate and indium(III) chloride, respectively. Indium metal serves for exclusive deprotection and reductive demonochlorination of 2,2,2-trichloroethyl esters, highly depending on structural features of the substrates.