Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
STUDIES ON THE EFFECTS AND FUNCTION MECHANISM OF ROTOMIN ON LEPROSY AND RRT LEPROSY
Shinji NishimuraMichiyuki Kono[in Japanese]
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JOURNAL FREE ACCESS

1950 Volume 19 Issue 6 Pages 22-23

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Abstract

1) The results of from 40 to 116 subcutaneous injections of 0.1ce protomin to 17 rats with leprosy were as following. Aggravation 6, no change 6, inprovement 4, recovery 1. We recognized no effect.
2) Intravenous injections to 13 tubercle and eleven macula patients showed a hopeful result, though the observation was for a short while.
3) The density of protomin in the blood both of men and rats rapidly decreased after the injection.
4) The density of free diamino-diphenyl sulfone was much lower in rats than in men.
5) The mean average value of distribution of diamino-diphenyl sulfone in every organof a rat was highest in liver and kidney, then in skin and blood and lowest in lung spleen and brain.

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