1959 Volume 28 Issue 5 Pages 214-219
C-strain rats were inoculated with 0.4 cc of 50 x live muri-lepra bacilli solution ; and with the untreated rats with normal salivary glands, subcutaneously inoculated with live muri-lepra bacilli as the control group, the influence of asialadenism and hypersialadenism at the time of subcutaneous inoculation of muri-lepra bacilli in regard to infection towards murine leprosy was observed over a short period (7 wks.) and over a moderate period (15 wks.).
In the skin leproma, inoculated with live muri-lepra bacilli and in the lymph glands, spleen, liver and lungs, similar to Report I, the muri-lepra change is strongly inhibited in the hypersialadenism group as compared with the normal salivary glands untreated group, shows a tendency towards aggravation in the asialadenismus group, and at the same time the hyperfunction of the reticulo-endothelial system cells can be seen. That is to say, asialadenismus group untreated normal group hypersialadenismus group.
In this experiment, the difference was not so marked between the various groups in regard to the skin muri-leproma, but showed comparatively marked differences in the visceral phase.
