Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
STUDIES ON THE INFECTIONS MECHANISMS OF MURINE LEPROSY
Part II. The Influence of Anti-monocyte Serum on Murine Leprosy
Masakazu SUZUKI
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1959 Volume 28 Issue 6 Pages 324-330

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Abstract
One hundred and twenty-six rats were used in this experiment. The author employed the anti-monocyte serum obtained from rabbits which were sensitized by intraperitoneal monocyte of rats.
The host cells of murine leprosy bacilli were injuried by reversed-allergic reaction caused by this serum. In intraperitoneally inoculated murine leprosy, multiplication of murine leprosy bacilli in the intraperitoneal monocyte of the group was inhibited markedly as compared with control group and the bacilli left early the cells.
In autopsy cases after 40 days of each group, development of leproma was inhibited markedly in the group. After five months the autopsy showed the inhibition of the dissemination of bacilli. Exceptionally, in a group which injected with liquid paraffin before the injection of serum, multiplication of murine leprosy bacilli was inhibited as compared with untreated group.
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