1960 Volume 29 Issue 5-6 Pages 232-238
Antigenicity of pyridin extract of Kedrowsky bacillus prepared by Chatterjee's original method was compared with that of Dharmendra antigen in sensitized animals and in leprosy patients.
1. Pyridin extract of Kedrowsky bacillus contains much amount of polysaccharide and rather small amount of protein.
2. Intradermal reaction was tested on three groups of animals sensitized either with heatkilled Kedrowsky bacillus, tubercle bacillus or human leprosy bacillus respectively. The results revealed that the reaction provoked by the Kedrowsky bacillus was specific. Human leprosy bacillus did not show any positive reaction in the animals sensitized with Kedrowsky bacillus and pyridin extract of this microbe gave no positive reaction in those sensitized with human leprosy bacillus.
3. Correlation between the pyridin extract as well as PPD of Kedrowsky bacillus and the Dharmendra antigen was found to be very low also in the leprosy patients.
