Intrajoint Inoculation of Myc. leprae and lepraemurium to the Mouse

Abstract

The fate of Myc. leprae and lepraemurium followed by the mouse-joint inoculation which had not been attempted before was observed and the results obtained demonstrated that Myc. lepraemurium developed well in the foot-joint cavity. The part of the bacillus multipliaction was the joint-sack, not joint fluid. No additional effects of mucine, crystal violet, and trypan blue to the bacillary suspension for stimulating the development of the bacilli were observed.
In the case of Myc. leprae experiments, there were no increases of the bacilli in this part, when observed direct smear preparations. However, the further experiments shoud be needed for the determination of the increases of the bacilli, because, in this experiment, the number of bacilli in the materials was not mathe- matically calculated.