Abstract
1) The author injected into the abdominal cavity of young rats 0.2cc of an emulsion of a nodule of rat lepra, which is suspended with 20 times water. After 8 months in all of 3 cases pathological changes of the eye were observed.
2) In these cases quite severe pathological changes in various visceras were noticed and numerous bacilli in subcutaneous lymphatic glands. The pathological changes in the skin surrounding the orbita were severer than that of the back. This fact indicated that the eye is a place of praedilection of rat lepra.
3) The seat of praedilection of the disease in the eye is as follows-conjunctiva palperae, palpebra, limbus episclerae, conjunctiva bulbi, environs of eye-ball, glandtissue and environs of n. opticus. But no bacilli were found in cornea, tissue of internal eyes and n. opticus. Shortly, pathological changes of the eye were noticed in the eyelid, environs of the eyeball and the surface of the frontal hemisphere of the eyeball. Changes of the eyeball in experimental animals seem to occur in the frontal half of the eyeball as seen in leprous rats or human leprosy and to come continuously from the skin surrounding the orbita, but not throgh the blocd metastatically. (Abstracted by the author)
