Abstract
Following the Road Traffic Act revised in June 2002, disqualification provisions have been applied to medical conditions of dementia including Alzheimer's disease and vascular dementia. On the other hand, those with cognitive and/or behavioral problems following traumatic brain injury, cerebrovascular diseases, encephalitis, etc. are relative, but not absolute disqualification reasons for driving license. However, there exist no decisive clinical criteria that determine the driving fitness of so-called “higher brain dysfunction” individuals. In this article, activities and situations of the driving evaluation clinic at Showa University were introduced and several characteristic individuals with higher brain dysfunction were reviewed. It is of great importance that we consider multidisciplinary approaches for the safety of automobile driving of cognitively handicapped individuals.