2021 Volume 10 Issue 1 Pages 58-65
It has already been more than 30 years since the first cord blood transplantation in France. During this period, the position of cord blood transplantation has been changing, given the decreased incidence of graft failure or identification of powerful GVL effect. Despite the decrease in the annual number of cord blood transplantation in both the US and the EU, mostly due to increased transplants from haploidentical donors, cord blood transplantations are still increasing in Japan. Better management of early complications, infections or alloimmune reactions in particular, and disease recurrence after cord blood transplant would be vital to improving the outcomes.
