Abstract
Resorcinol cyclic tetramer (also calix[4]resorcinarene) as host 1 interact with monosaccharides in apolar solvent such as CHCl3 or CCl4 . However, this interaction is very weak because host 1 has low polarity. We synthetized resorcinol cyclic tetramer derivatives having high polarity as novel host molecules, and investigated molecular recognition host-saccharide interaction. As a result, we discovered that the novel host molecules interacted with saccharides strongly by host-guest hydrogen-bonding.
