Evaluation of biological moleculer adsorption on hydroxyapatite and amorphus Ca₁₀(PO₄)₆(OH)₂ thin films using QCM method

Abstract

Biological molecular adsorption on crystal hydroxyapatite (HAp) and amorphous Ca₁₀(PO₄)₆(OH)₂ was investigated using quartz crystal microbalance (QCM) method. The pulsed laser ablation (PLA) was applied to coat both kind films for QCM sensors. A crystal HAp sensor was prepared with thermal treatment during the fabrication process. An amorphous Ca₁₀(PO₄)₆(OH)₂ sensor was prepared without any thermal treatment. Not only crystal HAp but amorphous Ca₁₀(PO₄)₆(OH)₂ showed good adsorptive feature compared with conventional QCM on the market. The result showed that a low temperature deposition of HAp is adaptable to polymer-based materials for medical purposes.