Study of Cell Adhesion of CNTs for the Development of Electrodes with Superior Biocompatibility and Electrical Properties

Abstract

Studying biological activities over an extended period is essential for a deeper understanding of human physiological function including brain plasticity. However, meeting this requirement demands a highly biocompatible device with favorable electrical properties. Hence, carbon nanotubes (CNTs) emerge as a suitable material for electrodes due to their exceptional electrical conductivity and ability to enhance electrode surface area. In our research, we initially apply a polyethyleneimine (PEI) coating to the glass substrate to enhance the interfacial adhesion between the CNTs and the substrate. Subsequently, we culture mouse myoblast cells (C2C12) on the CNT-coated glass substrate to illustrate that CNTs have minimal impact on cell adhesion and are therefore suitable for use as electrodes.