Electrical Equivalent Circuit and Resting Membrane Potential of Neuron

Abstract

New equivalent circuits of neuron, different from the equivalent circuit of Hodgkin-Huxley, are proposed. In these circuits, ion-condensers are a concept to represent the equilibrium potential of ions, and power sources to represent ion-pumps. Uning these equivalent circuits, we derive the equations which relate the resting membrane potential with capacity of the ion-pumps, intracellular impermeant anions concentrations, extracellular ions concentrations and permeability of ions transported by the ion-pumps. Using these equations, we elaluate the effect of presence of intracellular impermeant anions on the resting membrane potential