Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
Morphological and Histochemical Observations on Right Ventricular Outflow Tract of Tetralogy of Fallot
With a Brief Reference to Hemodynamic Viewpoint (I)
Isao SAKASHITAEiichiro AOKITetsunosuke MATSUKAWAKen-ichi ASANO
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1969 Volume 10 Issue 5 Pages 395-408

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Abstract
Hemodynamic, morphological and functional observations on the right ventricular outflow tract of tetralogy of Fallot were performed. The classification of the structures of the outflow tract into 3 types (I-localized infundibular hypertrophy, II-valvular stenosis and III-hypoplasia of the pulmonary trunk combined with infundibulovalvular stenosis) might be suitable and practical from the points of hemodynamic and angiocardiographic studies.
Morphological, histochemical and electron microscopic findings obtained in this survey revealed characteristic patterns shown in the dystrophied cardiac muscle structures secondary to possible hypertrophy. During the studies, effects of congenital cyanosis or intracardiac pressure on structures of the outflow tract of tetralogy of Fallot were found to be taken into consideration to locate a position as to hypertrophied or dystrophied muscle. Further investigations are necessitated in these points with more distinct presentations of cardiac nerve innervation.
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