Development of Sympathetic Nervous System in Stroke-prone SHR (SHRSP)

Abstract

The noradrenergic fluorescence at the nerve terminals was augmented during the ontogenic development in the mesenteric arteries, cerebrobasal arteries and renal arteries of SHRSP. The finding suggests that the sympathetic aminergic neuron system may be altered genetically in SHRSP. The nervous system in young SHRSP may accelerate the vasomotion of systemic and cerebral afteries, leading to severe hypertensive vascular lesions observed in adult SHRSP