Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
On Hypotensive Substances in Plants (II)
Tetsuo MurakamiYoshitomi IizukaKazuaki KakehiSusumu HondaHideo MiyakeKozo Okamoto
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1981 Volume 22 Issue 3 Pages 497

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Abstract
Screening tests for hypotensive substances were conducted on 57 items from 50 plants. Intravenous administration of fractions from Solidago altissima L. (leaves), asparagus, okra, cornhusk, corncob, tassel and bamboo leaves showed falls in blood pressure in SHR and SHRSP, especially the first marked and continuous falls. Furthermore, extracts from Solidago altissima L. and cornhusk were fractionated on columns of silica gel and Sephadex G-50. The crystalline compounds in the cornhusk fraction were identified as adenosine and guanosine. In addition, the hypotensive substance of fraction A1 from Solidago altissima L. may be a glycoprotein with a molecular weight of over 10, 000.
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© by International Heart Journal Association
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