Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
Changes in Catecholaminergic Neurons in Medulla Oblongata of Spontaneously Hypertensive rat
M. OhtsujiM. Nomura
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1984 Volume 25 Issue 5 Pages 854

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Abstract
We determined catecholamine (CA) content in brain of spontaneously hypertensive rat (SHR) and observed a decrease of noradrenarine (NA) content in the brain stem as previous report. Then we used Glutaraldehyde-formaldehyde fluorescence method for histochemical study. Fluorescence of ventral Al and dorsal A2 cell bodies in medulla oblongata was decreased. NA accumulation in caudal nervous ending of nucleus tractus solitarius (NTS) was reduced in SHR of pre-hypertensive stage aged 4 weeks. There were no changes in other regions, thalamus, hypothalamus, substantia nigra, locus ceruleus and periventricular nucleus.
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