Abstract
The alterations of renal blood flow measured by an electromagnetic flowmeter were observed in the perfused dog kidney innervated in situ in various conditions. The method of perfusion was improved to reduce the resistance in the circuit and to avoid the possibility of damage in nervous tissue and of renal ischemia during manipulations which were accompanied by some difficulties in our previous study. Following results were confirmed:
(1) In electrical stimulation of the distal end of the divided cervical vagal nerve, renal vasoconstriction was produced.
(2) By occlusion of common carotid arteries, renal vasoconstriction occurred.
(3) Giving a high pressure on the carotid sinus caused no alteration in renal vascular vessels.
(4) On stimulation of the central end of the divided subclavian nerve, the renal blood vessels showed various responses.
(5) On stimulation of the central end of the divided cervical vagal nerve, the attitude of renal vascular vessels was also variable.
(6) Alteration in perfusion pressure caused parallel change in renal blood flow and effect of the autoregulatory mechanism on renal circulation could not be demonstrated.
