Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope
Masato TSUTSUITakeyuki MATSUGUCHIHiroyuki TSUTSUITetsuhiko YOSHIDAShingo YOSHIHARAKunihiko YAMAMOTORyuichi HISANOUHiroaki SHIMOKAWAShuichi OKAMATSU
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1992 Volume 33 Issue 6 Pages 875-879

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Abstract

We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcoholinduced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.

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